About Phenylephrine Hydrochloride(Oral and Injectable)

Therapeutic Category

Decongestant

Dose Form

Oral and Injectable

Status

Commercialised

Available Regulatory Filing

CEP Filed

CAS No

61-76-7

Pharmacopoeia

IP/USP/EP

Mechanism of Action

Phenylephrine hydrochloride is a selective alpha-1 adrenergic agonist that primarily acts on vascular smooth muscle. By stimulating alpha-1 adrenergic receptors, it causes vasoconstriction, leading to increased systemic vascular resistance and elevated blood pressure. This mechanism makes it effective as a decongestant and in managing hypotension during anesthesia.

Indication

Indicated as a decongestant for temporary relief of nasal congestion due to colds, allergies, and hay fever, and for the relief of sinus congestion and pressure.

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