Top 10 Active Pharmaceutical Ingredients

Active Pharmaceutical Ingredients (APIs) are the cornerstone of modern medicine, forming the essential component of any pharmaceutical formulation. Valence Labs stands as a trusted name in the pharmaceutical industry, offering a wide range of high-quality APIs tailored for various therapeutic categories. In this blog, we explore the Top 10 Active Pharmaceutical Ingredients manufactured by Valence Labs, their therapeutic benefits, and the current status of their development and commercialization.

List of Top 10 Active Pharmaceutical Ingredients in India

1. Phenylephrine Hydrochloride

• CAS No: 61-76-7
• Therapeutic Category: Decongestant
• Pharmacopoeia Compliance: IP/USP/EP
• Status: Commercialised (CEP Filed)

Phenylephrine Hydrochloride is a widely used decongestant effective in relieving nasal congestion caused by colds, allergies, and sinus infections. Its multi-pharmacopoeia compliance ensures its suitability for global markets. With a CEP filing underway, Valence Labs ensures its API quality meets international standards.

2. Dexketoprofen Trometamol

• CAS No: 156604-79-4
• Therapeutic Category: Anti-Inflammatory
• Pharmacopoeia Compliance: In-House
• Status: Commercialised (DMF Available)

Dexketoprofen Trometamol is an anti-inflammatory API that provides rapid pain relief and reduces inflammation. Its in-house development and DMF availability highlight Valence Labs’ dedication to offering cutting-edge APIs for pain management.

3. Dapagliflozin Propanediol

• CAS No: 960404-48-2
• Therapeutic Category: Antidiabetic
• Pharmacopoeia Compliance: USP/In-House
• Status: Commercialised (DMF Available)

This antidiabetic API, Dapagliflozin Propanediol, is a Sodium-Glucose Co-Transporter-2 (SGLT2) inhibitor that helps manage Type 2 diabetes by regulating blood sugar levels. Its USP compliance and DMF availability underscore its reliability and global acceptability.

4. Dapagliflozin Amorphous

• CAS No: 461432-26-8
• Therapeutic Category: Antidiabetic
• Pharmacopoeia Compliance: In-House
• Status: Commercialised

As a variation of Dapagliflozin, the Amorphous form offers enhanced bioavailability. It plays a critical role in improving glycemic control in diabetes patients, demonstrating Valence Labs’ innovative approach to API development.

5. Fexofenadine Hydrochloride

• CAS No: 153439-40-8
• Therapeutic Category: Antihistaminic
• Pharmacopoeia Compliance: IP/USP/EP/JP
• Status: Commercialised (CEP Filing in Q3 FY25)

Fexofenadine Hydrochloride is a non-drowsy antihistamine used to alleviate symptoms of allergies, such as hay fever and chronic hives. Its multi-pharmacopoeia compliance and pending CEP filing demonstrate its premium quality and global market readiness.

6. Citicoline Sodium

• CAS No: 33818-15-4
• Therapeutic Category: Psychostimulant
• Pharmacopoeia Compliance: IP/USP
• Status: Commercialised

Citicoline Sodium enhances cognitive function and memory, making it a valuable API for treating neurological conditions. Its compliance with IP and USP standards highlights Valence Labs’ commitment to excellence.

7. Ursodeoxycholic Acid

• CAS No: 128-13-2
• Therapeutic Category: Cholelithiasis Agent
• Pharmacopoeia Compliance: IP/USP/EP
• Status: Commercialised (DMF Available in Q3 FY25)

Ursodeoxycholic Acid is instrumental in treating liver-related disorders, including gallstone dissolution and primary biliary cholangitis. Its pharmacopoeia compliance ensures its efficacy and safety for widespread therapeutic use.

8. Nicotine

• CAS No: 54-11-5
• Therapeutic Category: Stimulant
• Pharmacopoeia Compliance: Stimulant
• Status: Validation in Q3 FY25

As a stimulant API, Nicotine is primarily used in smoking cessation products. Valence Labs is currently validating this API, ensuring adherence to the highest industry standards for upcoming commercial availability.

9. Tolvaptan

• CAS No: 150683-30-0
• Therapeutic Category: Diuretic
• Pharmacopoeia Compliance: IP/In-House
• Status: Validation in Q3 FY25

Tolvaptan is a diuretic API used to treat hyponatremia (low sodium levels) and polycystic kidney disease. Its validation phase indicates that it will soon become a key offering in the API market.

10. Ketoprofen

• CAS No: 22071-15-4
• Therapeutic Category: Anti-Inflammatory
• Pharmacopoeia Compliance: USP/EP
• Status: Developed at Lab Scale

Ketoprofen is another significant anti-inflammatory API by Valence Labs. It is commonly used in pain management and inflammation reduction, showcasing their capabilities in producing lab-scale developed APIs for diverse applications.

Why Choose Valence Labs?

Valence Labs is a leading pharmaceutical manufacturer committed to delivering superior quality APIs. Here’s why they are a preferred choice for global pharmaceutical companies:

1. Multi-Pharmacopoeia Compliance: Their APIs meet stringent standards, including IP, USP, EP, and JP.
2. Innovative R&D: A strong focus on in-house development and state-of-the-art facilities ensures top-quality products.
3. Regulatory Excellence: With CEP filings and DMF availability, Valence Labs is dedicated to meeting global regulatory requirements.
4. Diverse Therapeutic Categories: From antidiabetic and anti-inflammatory to psychostimulants and decongestants, their APIs cater to various medical needs.

Conclusion

Valence Labs’ top 10 active pharmaceutical ingredients reflect their commitment to innovation, quality, and therapeutic diversity. These APIs address critical healthcare needs across a spectrum of therapeutic categories, ensuring safety, efficacy, and global compliance. Whether you are seeking antidiabetic solutions like Dapagliflozin, anti-inflammatory options like Dexketoprofen, or psychostimulants like Citicoline Sodium, Valence Labs offers high-quality APIs tailored to your requirements.

Choose Valence Labs as your trusted API partner to deliver superior pharmaceutical solutions and drive innovation in healthcare.